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Manuscripts, Abstracts, & Letters to the Editor
Manuscripts
1. Moore W. Issues to Be Addressed and Hopefully Resolved in the Carotid Revascularization Endarterectomy Versus Stenting Trial 2. Angiology. 2016;67:408-410. [PMCID: 26460327]
2. Marulanda-Londono E, Chaturvedi S. Stroke due to large vessel atherosclerosis. Neurol Clin Pract. 2016;6:252-258.
3. Chaturvedi S, Chimowitz M, Brown RD Jr, Lal BK, Meschia JF. The urgent need for contemporary clinical trials in patients with asymptomatic carotid stenosis. Neurology. 2016;87(21):2271-2278. [PMCID: 5123552]
4. Howard VJ, Meschia JF, Lal BK, Turan T, Roubin G, Brown RD Jr, Voeks J, Barrett KM, Demaerschalk BM, Huston III J, Lazar R, Moore W, Wadley VG, Chaturvedi S, Moy CS, Chimowitz M, Howard G, and Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: Protocol of the CREST-2 Clinical Trials. International Journal of Stroke. 2017;12(7):770-778. [PMID: 28462683]
5. Demaerschalk BM, Brown RD, Roubin GS, Howard VJ, Cesko E, Barrett KM, Longbottom ME, Voeks JH, Chaturvedi S, Brott TG, Lal BK, Meschia JF, Howard G, for the CREST-2 Investigators. Factors Associated with Time to Site Activation, Randomization, and Enrollment Performance in a Stroke Prevention Trial. Stroke. 2017;48(9):2511-2518. [PMCID: 5575963]
6. Lal BK, Meschia JF, Brott TG. Clinical need, design, and goals for the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis trial. Seminars in Vascular Surgery. 2017;30:2-7. [PMID: 28818255]
7. Heck DV, Roubin GS, Rosenfield KG, Gray WA, White CJ, Jovin TG, Matsumura JS, Lal BK, Katzen BT, Dabus G, Jankowitz BT, Brott TG. Asymptomatic carotid stenosis: Medicine alone or combined with carotid revascularization. Neurology. 2017;88:2061-2065. [PMCID: 5440242]
8. Meschia JF, Klaas JP, Brown RD Jr, Brott TG. [Meschia, 2017 #2]Evaluation and Management of Atherosclerotic Carotid Stenosis. Mayo Clinic Proceedings. 2017;92(7):1144-1157. [PMCID: 5576141]
9. Lal BK, Meschia JF, Roubin GS, Jankowitz BT, Heck DV, Jovin TG, White CJ, Rosenfield K, Katzen B, ; Dabus G, Gray W, Matsumura J, Hopkins LN, Luke S, Sharma J, Voeks JH, Howard G, Brott TG, for the CREST-2 Investigators. Factors influencing Credentialing of Interventionists in the CREST-2 Trial. Journal of Vascular Surgery. 2019; S0741-5214(19)31449-1. doi: 10.1016/j.jvs.2019.05.035. [Epub ahead of print] [PMCID: 6980974]
10. Lal BK, Roubin GS, Rosenfield K, Heck D, Jones M, Jankowitz B, Jovin T, Chaturvedi S, Dabus G, White CJ, Gray W, Matsumura J, Katzen BT, Hopkins LN, Mayorga-Carlin M, Sorkin JD, Howard G, Meschia JF, Brott TG “Quality Assurance for Carotid Stenting in the CREST-2 Registry.” Journal of the American College of Cardiology 2019;74(25):3071-3079. [PMCID:7012370]
11. Meschia JF, Barrett KM, Turan TN, Brown RD Jr, Howard VJ, Voeks JH, Lal BK, Howard G, Brott TG. “The CREST-2 experience with the evolving challenges of COVID-19: A clinical trial in a pandemic.” Neurology. 2020;95(1):29-36. [PMID: 32358216] [PMID: PMC7371383]
12. Turan TN, Voeks JH, Chimowitz MI, Roldan A, LeMatty T, Haley W, Lopes-Virella M, Chaturvedi S, Jones M, Heck D, Howard G, Lal BK, Meschia JF, Brott TG. “Rationale, Design, and Implementation of Intensive Risk Factor Treatment in CREST2.” Stroke. 2020;51:2960-2971. [PMCID:7530035]
13. Turan TN, Meschia JF, Chimowitz MI, Eiland R, Foley J, Brott TG. “Mitigating the effects of COVID-19 pandemic on controlling vascular risk factors among participants in a carotid stenosis trial.” Journal of Stroke and Cerebrovascular Diseases. 2020 Sep 30, epub ahead of print. [PMCID:7524666]
14. Lal BK, Meschia JF, Brott TG, Jones M, Aronow HD, Lackey A, Howard G. “Race Differences in High-Grade Carotid Artery Stenosis.” Stroke. 2021; May 4; doi: 10.1161/STROKEAHA.120.032723. [EPub ahead of print]
15. Lazar RM, Wadley VG, Myers T, Jones MR, Heck DV, Clark W, Marshall RS, Howard VJ, Voeks JH, Manly JJ, Moy CS, Chaturvedi S, Meschia JF, Lal BK, Brott TG, Howard G. “Baseline Cognitive Impairment in Patients with Asymptomatic Carotid Stenosis in the CREST-2 Trial.” Stroke. 2021, Accepted for publication
16. Haley W, Shawl F, Sternbergh WC, Turan T, Barrett K, Voeks JH, Brott TG, Meschia J. “Patterns of Antihypertensive Drug Use in Patients with Asymptomatic Carotid Stenosis.” Journal of Stroke and Cerebrovascular Diseases 2021, Accepted for publication
17. Haley W, Shawl F, Sternbergh WC, Turan T, Barrett K, Voeks JH, Brott TG, Meschia J. “Non-Adherence to Antihypertensive Guidelines in Patients with Asymptomatic Carotid Stenosis.” Journal of Stroke and Cerebrovascular Diseases 2021;30, Jun 18. EPub ahead of print [PMID: 34148021]
18. Lal BK, Meschia JF, Jones M, Aronow HD, Lackey A, Lake R, Howard G, Brott TG. “Health screening program to enhance enrollment of women and minorities in a national trial: Experiences from CREST-2.” Stroke. 2021, Submitted (revision requested)
1. Moore W. Issues to Be Addressed and Hopefully Resolved in the Carotid Revascularization Endarterectomy Versus Stenting Trial 2. Angiology. 2016;67:408-410. [PMCID: 26460327]
2. Marulanda-Londono E, Chaturvedi S. Stroke due to large vessel atherosclerosis. Neurol Clin Pract. 2016;6:252-258.
3. Chaturvedi S, Chimowitz M, Brown RD Jr, Lal BK, Meschia JF. The urgent need for contemporary clinical trials in patients with asymptomatic carotid stenosis. Neurology. 2016;87(21):2271-2278. [PMCID: 5123552]
4. Howard VJ, Meschia JF, Lal BK, Turan T, Roubin G, Brown RD Jr, Voeks J, Barrett KM, Demaerschalk BM, Huston III J, Lazar R, Moore W, Wadley VG, Chaturvedi S, Moy CS, Chimowitz M, Howard G, and Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: Protocol of the CREST-2 Clinical Trials. International Journal of Stroke. 2017;12(7):770-778. [PMID: 28462683]
5. Demaerschalk BM, Brown RD, Roubin GS, Howard VJ, Cesko E, Barrett KM, Longbottom ME, Voeks JH, Chaturvedi S, Brott TG, Lal BK, Meschia JF, Howard G, for the CREST-2 Investigators. Factors Associated with Time to Site Activation, Randomization, and Enrollment Performance in a Stroke Prevention Trial. Stroke. 2017;48(9):2511-2518. [PMCID: 5575963]
6. Lal BK, Meschia JF, Brott TG. Clinical need, design, and goals for the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis trial. Seminars in Vascular Surgery. 2017;30:2-7. [PMID: 28818255]
7. Heck DV, Roubin GS, Rosenfield KG, Gray WA, White CJ, Jovin TG, Matsumura JS, Lal BK, Katzen BT, Dabus G, Jankowitz BT, Brott TG. Asymptomatic carotid stenosis: Medicine alone or combined with carotid revascularization. Neurology. 2017;88:2061-2065. [PMCID: 5440242]
8. Meschia JF, Klaas JP, Brown RD Jr, Brott TG. [Meschia, 2017 #2]Evaluation and Management of Atherosclerotic Carotid Stenosis. Mayo Clinic Proceedings. 2017;92(7):1144-1157. [PMCID: 5576141]
9. Lal BK, Meschia JF, Roubin GS, Jankowitz BT, Heck DV, Jovin TG, White CJ, Rosenfield K, Katzen B, ; Dabus G, Gray W, Matsumura J, Hopkins LN, Luke S, Sharma J, Voeks JH, Howard G, Brott TG, for the CREST-2 Investigators. Factors influencing Credentialing of Interventionists in the CREST-2 Trial. Journal of Vascular Surgery. 2019; S0741-5214(19)31449-1. doi: 10.1016/j.jvs.2019.05.035. [Epub ahead of print] [PMCID: 6980974]
10. Lal BK, Roubin GS, Rosenfield K, Heck D, Jones M, Jankowitz B, Jovin T, Chaturvedi S, Dabus G, White CJ, Gray W, Matsumura J, Katzen BT, Hopkins LN, Mayorga-Carlin M, Sorkin JD, Howard G, Meschia JF, Brott TG “Quality Assurance for Carotid Stenting in the CREST-2 Registry.” Journal of the American College of Cardiology 2019;74(25):3071-3079. [PMCID:7012370]
11. Meschia JF, Barrett KM, Turan TN, Brown RD Jr, Howard VJ, Voeks JH, Lal BK, Howard G, Brott TG. “The CREST-2 experience with the evolving challenges of COVID-19: A clinical trial in a pandemic.” Neurology. 2020;95(1):29-36. [PMID: 32358216] [PMID: PMC7371383]
12. Turan TN, Voeks JH, Chimowitz MI, Roldan A, LeMatty T, Haley W, Lopes-Virella M, Chaturvedi S, Jones M, Heck D, Howard G, Lal BK, Meschia JF, Brott TG. “Rationale, Design, and Implementation of Intensive Risk Factor Treatment in CREST2.” Stroke. 2020;51:2960-2971. [PMCID:7530035]
13. Turan TN, Meschia JF, Chimowitz MI, Eiland R, Foley J, Brott TG. “Mitigating the effects of COVID-19 pandemic on controlling vascular risk factors among participants in a carotid stenosis trial.” Journal of Stroke and Cerebrovascular Diseases. 2020 Sep 30, epub ahead of print. [PMCID:7524666]
14. Lal BK, Meschia JF, Brott TG, Jones M, Aronow HD, Lackey A, Howard G. “Race Differences in High-Grade Carotid Artery Stenosis.” Stroke. 2021; May 4; doi: 10.1161/STROKEAHA.120.032723. [EPub ahead of print]
15. Lazar RM, Wadley VG, Myers T, Jones MR, Heck DV, Clark W, Marshall RS, Howard VJ, Voeks JH, Manly JJ, Moy CS, Chaturvedi S, Meschia JF, Lal BK, Brott TG, Howard G. “Baseline Cognitive Impairment in Patients with Asymptomatic Carotid Stenosis in the CREST-2 Trial.” Stroke. 2021, Accepted for publication
16. Haley W, Shawl F, Sternbergh WC, Turan T, Barrett K, Voeks JH, Brott TG, Meschia J. “Patterns of Antihypertensive Drug Use in Patients with Asymptomatic Carotid Stenosis.” Journal of Stroke and Cerebrovascular Diseases 2021, Accepted for publication
17. Haley W, Shawl F, Sternbergh WC, Turan T, Barrett K, Voeks JH, Brott TG, Meschia J. “Non-Adherence to Antihypertensive Guidelines in Patients with Asymptomatic Carotid Stenosis.” Journal of Stroke and Cerebrovascular Diseases 2021;30, Jun 18. EPub ahead of print [PMID: 34148021]
18. Lal BK, Meschia JF, Jones M, Aronow HD, Lackey A, Lake R, Howard G, Brott TG. “Health screening program to enhance enrollment of women and minorities in a national trial: Experiences from CREST-2.” Stroke. 2021, Submitted (revision requested)
19. Brott, T. G., Meschia, J. F., Lal, B. K., Chamorro, Á., Howard, V. J., & Howard, G. (2023). When will we have what we need to advise patients how to manage their carotid stenosis?: Lessons from space-2. Stroke, 54(5), 1452–1456. https://doi.org/10.1161/strokeaha.122.042172 [PMID: 36942589] [PMID: PMC10133171 (available on 2024-05-01)]
20. Marshall RS, Liebeskind DS, Huston J III, Edwards LJ, Howard G, Meschia JF, Brott TG, Lal BK, Heck D, Lanzino G, Sangha N, Kashyap VS, Morales CD, Cotton-Samuel D, Rivera AM, Brickman AM, Lazar RM. “Cortical Thinning in High-grade Asymptomatic Carotid Stenosis.” Journal of Stroke 2023 Jan;25(1): 92-100. [PMID: 36592969] [PMCID: PMC9911846]
21. Meschia JF, Lal BK, Roubin GS, Turan TN, Howard VJ, Benson RT, Carmen K, Howard G, Brott TG. “Adapting to Evolving Technologies and Treatment Guidelines in a Procedural Trial: The CREST-2 Experience.” Neurology 2023;100(22): 1060-1066. [PMID: 36746636][ PMCID: PMC10259285]
20. Marshall RS, Liebeskind DS, Huston J III, Edwards LJ, Howard G, Meschia JF, Brott TG, Lal BK, Heck D, Lanzino G, Sangha N, Kashyap VS, Morales CD, Cotton-Samuel D, Rivera AM, Brickman AM, Lazar RM. “Cortical Thinning in High-grade Asymptomatic Carotid Stenosis.” Journal of Stroke 2023 Jan;25(1): 92-100. [PMID: 36592969] [PMCID: PMC9911846]
21. Meschia JF, Lal BK, Roubin GS, Turan TN, Howard VJ, Benson RT, Carmen K, Howard G, Brott TG. “Adapting to Evolving Technologies and Treatment Guidelines in a Procedural Trial: The CREST-2 Experience.” Neurology 2023;100(22): 1060-1066. [PMID: 36746636][ PMCID: PMC10259285]
Abstracts
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update.American Neurology Association, 2014. Ann Neurol. 2014.
- Meschia JF, Lal BK, Howard G, Roubin G, Mackey A, Hill MD, Silver F, Demaerschalk BM, Brown RD Jr, Chimowitz M, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update.Canadian Stroke Congress, 2014. Stroke. 2014;45(12): e25.
- Lal BK, Rosenfield K, Furlan A, Heck D, Tunis S, Roubin G, Meschia JF, Howard G, Brott TG, for the CREST-2 Investigators. CREST-2 Companion Registry Update. ISET. 2015.
- Huston III J, Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Society of Neuroradiology (ASNR). 2015.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2015. Stroke. 2015.
- Lal BK, Rosenfield K, Heck D, Tunis S, Furlan A, Roubin G, Meschia JF, Howard G, Brott TG, for the CREST-2 Investigators. The CREST-2 Companion Registry: quality control for stenting and pathway to re-imbursement. International Stroke Conference, 2015. Stroke. 2015.
- Barrett KM, Moy C, Brown RD Jr, Broderick J, Spilker J, Linke M, Lal BK, Howard G, Brott TG, Meschia JF, for the CREST-2 Investigators. CREST-2 and StrokeNet Collaboration – Early Experience.International Stroke Conference, 2015. Stroke. 2015.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update. American Neurology Association 2015. Ann Neurol. 2015
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update. American Heart Association Scientific Sessions. 2015.
- Lanzino G, Meschia JF, Lal BK, Howard G, Roubin GS, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz MI, Demaerschalk BM, Howard VJ, Huston III J, Lazar RM, Moore WS, Moy C, Turan TN, Voeks JH, Brott TG, for the CREST-2 Investigators.CREST-2:A Randomized Trial Comparing Carotid Revascularization and Medical Management as Treatment for Asymptomatic Carotid Stenosis. World Federal of Neurosurgical Societies. 2015.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2016. Stroke. 2016.
- Lal BK, Rosenfield K, Heck D, Chaturvedi S, Tunis S, Meschia JF, Moy C,Conley R, NordstromK, Morris H, Roubin G, Brott TG for the CREST-2 Registry.CREST-2 Registry- A Pathway to Quality Control for Carotid Artery Stenting.International Stroke Conference, 2016. Stroke. 2016.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.American Indian Participation in Clinical Research: A Cultural Perspective Survey from a CREST-2 Site. American Academy of Neurology Annual Meeting, 2016. Neurology. 2016.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Neurological Association Annual Meeting, 2016. Ann Neurol. 2016.
- Demaerschalk BM, Brown RD, Howard VJ, Tom M, Longbottom ME, Voeks JH, Kadiric E, Meschia JF, and Brott TG for the CREST-2 Investigators.Selection and activation of sites in a large multi-center randomized clinical trial.International Stoke Conference, 2017. Stroke. 2017.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2017. Stroke. 2017.
- Roubin G, Heck D, White C, Rosenfield K, Dabus G, Jovin T, Jankowitz B, Katzen B, Gray W, Matsumura J, Hopkins LN, Gamble D, Voeks JH, Luke S, Lal BK, Meschia JF, and Brott TG. Credentialing of Interventionists in a Large Randomized Trial. International Stroke Conference, 2017. Stroke. 2017.
- Barrett KM, Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar RM, Moore W, Moy C, Turan TN, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update.American Academy of Neurology Meeting, 2017. Neurology. 2017.
- Demaerschalk BM, Brown RD, Howard VJ, Tom M, Longbottom ME, Voeks JH, Cesko E, Meschia JF, and Brott TG for the CREST-2 Investigators.Selection and activation of sites in a large multi-center randomized clinical trial.American Academy of Neurology Meeting, 2017. Neurology. 2017.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Neurological Association Annual Meeting, 2017. Ann Neurol. 2017.
- Turan TN, Voeks J, Barrett KM, Brown, Jr RD, Chaturvedi S, Chimowitz M, Demaerschalk B, Emmady P, Howard G, Howard VJ, Huston J III, Jones M, Lal BK, Lazar RM, Meschia JF, Moore W, Moy CS, Roldan AM, Roubin GS, Brott TG for the CREST-2 Investigators. Relationship Between Risk Factor Control and Physician Specialty in the CREST2 Trial. International Stoke Conference, 2018. Stroke. 2018.
- Meschia JF, Barrett KM, Roubin G, Heck D, Jones M, Wechsler L, Rapp JH, Turan TN, Demaerschalk BM, Lal BK, Voeks J, Howard G, Howard VJ, Brott TG for the CREST-2 Investigators. Control of vascular risk factors at baseline in CREST-2. International Stoke Conference, 2018. Stroke. 2018.
- Haley WE, Turan TN, Voeks JH, Meschia JF, Lal BK, Roubin G, Shawl F, and Brott TG. Patterns of Baseline Antihypertensive Medications in Patients with Asymptomatic Carotid Stenosis. National Kidney Foundation 2018 Spring Clinical Meeting. Am J Kidney Dis. 2018.
- Turan TN, Meschia JF, Voeks J, Barrett KM, Brown, Jr RD, Chaturvedi S, Chimowitz M, Demaerschalk B, Emmady P, Howard G, Howard VJ, Huston J III, Jones M, Lal BK, Lazar RM,Moore W, Moy CS, Roldan AM, Roubin GS, Brott TG for the CREST-2 Investigators. Relationship Between Risk Factor Control and Physician Specialty in the CREST2 Trial. American Academy of Neurology Annual Meeting, 2018. Neurology. 2018.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Academy of Neurology Annual Meeting, 2018. Neurology. 2018.
- Lazar RM, Wadley VG, Marshall RS, Howard G, Howard VJ, Meschia JF, Voeks JH, Yuan Y, Lal BK, Heck D, Jones M, Brott TG. Baseline cognitive function among participants in the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2). American Academy of Neurology Annual Meeting, 2018. Neurology. 2018.
- Meschia JF, Barrett KM, Roubin G, Heck D, Jones M, Wechsler L, Rapp JH, Turan TN, Demaerschalk BM, Lal BK, Voeks JH, Howard G, Howard VJ, Brott TG for the CREST-2 Investigators. Control of vascular risk factors at baseline in CREST-2. American Academy of Neurology Annual Meeting, 2018. Neurology. 2018.
- Howard VJ, Wadley VG, Wolff P, Zhang Y, Knopman D, Lal BK, Meschia JF, Voeks JH, Howard G, Brott TG, Lazar R. Methods, Successes and Lessons Learned from Centralized Cognitive Assessment in a Multicenter Clinical Trial of Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis (CREST-2). Society for Clinical Trials Annual Meeting, 2018. SCT Journal. 2018
- Linke M, Brott TG, Pivovarova E, Meschia JF, Luke S, Roll S, Broderick J. Single IRB Review and Improves Approval Times for a NIH-funded Multi-Site Study. PRIM&R 2018 Advancing Ethical Research Conference. 2018
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Neurological Association Annual Meeting, 2018.
- Turan TN, Chimowitz MI, Roldan A, LeMatty T, Haley WE, Lopes-Virella M, Voeks JH, Zhang Y, Chaturvedi S, Foster M, Sharma M, Mehta R, Bradley N, Shaw F, Dobrovolny CL, Magee T, Lazar R, Meschia JF, Lal BK, Howard G, Howard VJ, Brott TG, for the CREST2 Investigators. Multimodal Risk Factor Management in Two Parallel Trials Comparing Revascularization with Intensive Medical Therapy for Asymptomatic Carotid Stenosis. Oral abstract presented at 34th World Congress of Internal Medicine, 2018.
- Howard VJ, Wadley VG, Wolff P, Zhang Y, Knopman D, Lal BK, Meschia JF, Voeks JH, Howard G, Brott TG, Lazar R. Methods, Successes and Lessons Learned from Centralized Cognitive Assessment in a Multicenter Clinical Trial of Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis (CREST-2). WCIM 2018 34th World Congress of Internal Medicine.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stoke Conference, 2019. Stroke. 2019.
- Brajesh K Lal, MD, Matthew Chrencik, BS, Amir A Khan, PhD, Michael Jones, MD, John Huston MD, Charles Sternbergh, MD,Joseph Rapp, MD, Dipankar Mukherjee, MD, Peter Henke, MD, John Yokemick, RVT, Wesley Moore, MD, Siddhartha Sikdar PhD,Jenifer Voeks PhD, George Howard DrPh, James Meschia, MD, Thomas Brott, MD. Carotid Plaque Characteristics to Baseline Vascular Risk Factors in a Large Randomized Trial: Results from the CREST-2 Trials. International Stroke Conference, 2019. Stroke. 2019
- Seemant Chaturvedi MD, Jenifer Voeks PhD, Tanya N Turan MD, MSc, Neil Gordon MD, Marc I Chimowitz MD, James F Meschia MD, Brajesh K Lal MD, George Howard DrPH, Gary S Roubin MD, PhD, Robert D Brown Jr, MD, Kevin M Barrett MD, Bart M Demaerschalk MD, Virginia J Howard PhD, John Huston III MD, Ronald M Lazar PhD, Wesley S Moore MD, Claudia S Moy PhD, and Thomas G Brott MD, for the CREST-2 Investigators. Baseline Physical Activity Profiles in the CREST-2 Randomized Trials. International Stroke Conference, 2019. Stroke. 2019
- Brajesh K Lal, MD, Matthew Chrencik, BS, Amir A Khan, PhD, Michael Jones, MD, John Huston MD, Charles Sternbergh, MD,Joseph Rapp, MD, Dipankar Mukherjee, MD, Peter Henke, MD, John Yokemick, RVT, Wesley Moore, MD, Siddhartha Sikdar PhD,Jenifer Voeks PhD, George Howard DrPh, James Meschia, MD, Thomas Brott, MD. Carotid Plaque Characteristics to Baseline Vascular Risk Factors in a Large Randomized Trial: Results from the CREST-2 Trials. American Academy of Neurology Annual Meeting, 2019. Neurology. 2019
- Seemant Chaturvedi MD, Jenifer Voeks PhD, Tanya N Turan MD, MSc, Neil Gordon MD, Marc I Chimowitz MD, James F Meschia MD, Brajesh K Lal MD, George Howard DrPH, Gary S Roubin MD, PhD, Robert D Brown Jr, MD, Kevin M Barrett MD, Bart M Demaerschalk MD, Virginia J Howard PhD, John Huston III MD, Ronald M Lazar PhD, Wesley S Moore MD, Claudia S Moy PhD, and Thomas G Brott MD, for the CREST-2 Investigators. Baseline Physical Activity Profiles in the CREST-2 Randomized Trials. American Academy of Neurology, Annual Meeting, 2019. Neurology. 2019
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Academy of Neurology, Annual Meeting, 2019. Neurology. 2019
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. 5th European Stroke Organization Conference, 2019.
- Lazar, RM, Wadley, VG, Marshall, RS, Howard, G, Howard V, Voeks, JH, Yuan, Y, Lal, BK, Meschia, J, Brott, T. Baseline cognitive function among participants in the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2). 5th European Stroke Organization Conference, 2019.
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Neurological Association Annual Meeting, 2019. Annals of Neurology. 2019
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2020. Stroke. 2020
- Chaturvedi S, Meschia JF, Lal BK, Howard G, Roubin, Turan T, Teal P, Brown RD Jr, Barrett K, Chimowitz M, Demaerschalk BM, Howard V, Huston J III, Lazar R, Moore W, Moy C, Voeks J, and Brott TG, for the CREST-2 Investigators. Frequency and Predictors of Polyvascular Disease in patients with symptomatic Carotid Stenosis. International Stroke Conference, 2020. Stroke. 2020
- Turan TN, Voeks J, Barrett KM, Brown, Jr RD, Chaturvedi S, Chimowitz M, Demaerschalk B, Emmady P, Howard G, Howard VJ, Huston J III, Jones M, Lazar RM, Moore W, Moy CS, Roldan AM, Roubin GS, Sangha N, Lal BK, Brott TG, Meschia JF, for the CREST-2 Investigators. Baseline Differences in Risk Factor Control and Medication Use Between 2 Trials Employing Intensive Medical Management (SAMMPRIS & CREST2). International Stroke Conference, 2020. Stroke. 2020
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stoke Conference, 2020. Stroke. 2020
- Turan TN, Voeks J, Barrett KM, Brown, Jr RD, Chaturvedi S, Chimowitz M, Demaerschalk B, Emmady P, Howard G, Howard VJ, Huston J III, Jones M, Lazar RM, Moore W, Moy CS, Roldan AM, Roubin GS, Sangha N, Lal BK, Brott TG, Meschia JF, for the CREST-2 Investigators. Baseline Differences in Risk Factor Control and Medication Use Between 2 Trials Employing Intensive Medical Management (SAMMPRIS & CREST2). American Academy of Neurology, Annual Meeting, 2020. Neurology. 2020
- Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Academy of Neurology, Annual Meeting, 2020. Neurology. 2020
- Chaturvedi S, Meschia JF, Lal BK, Howard G, Roubin, Turan T, Teal P, Brown RD Jr, Barrett K, Chimowitz M, Demaerschalk BM, Howard V, Huston J III, Lazar R, Moore W, Moy C, Voeks J, and Brott TG, for the CREST-2 Investigators. Frequency and predictors of disease in other vascular beds in patients with asymptomatic carotid stenosis: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis (CREST-2) . American Academy of Neurology, Annual Meeting, 2020. Neurology. 2020
- Meschia JF, Lal BK, Howard G, Jones M, Heck D, Turan TN, Roubin GS, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar RM, Moore WS, Moy C, Voeks JH, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stoke Conference, 2021. Stroke. 2021
- Chaturvedi S, Turan TN, Voeks JH, Goldstein J, Teal PA, Chimowitz MI, Barrett KM, Demaerschalk BM, Howard VH, Lazar RM, Moy CS, Moore WS, Roubin GS, Brown RD Jr, Meschia JF, Lal B, Howard G, Brott TG. Hypertriglyceridemia as a New Treatment Target in Asymptomatic Carotid Stenosis. Inernational Stoke Conference, 2021. Stroke. 2021
- Chaturvedi S, Turan TN, Voeks JH, Goldstein J, Teal PA, Chimowitz MI, Barrett KM, Demaerschalk BM, Howard VH, Lazar RM, Moy CS, Moore WS, Roubin GS, Brown RD Jr, Meschia JF, Lal B, Howard G, Brott TG. Hypertriglyceridemia as a New Treatment Target in Asymptomatic Carotid Stenosis. American Academy of Neurology, Annual Meeting, 2021. Neurology. 2021
- Chaturvedi S, Turan TN, Voeks JH, Goldstein J, Teal PA, Chimowitz MI, Barrett KM, Demaerschalk BM, Howard VH, Lazar RM, Moy CS, Moore WS, Roubin GS, Brown RD Jr, Meschia JF, Lal B, Howard G, Brott TG. Hypertriglyceridemia as a New Treatment Target in Asymptomatic Carotid Stenosis. American Academy of Neurology, Annual Meeting, 2021. Neurology. 2021
- Lal B, Meschia JF, Heck DV, Jones M, Howard G, Lloyd E, Brown R, Brott TG. Patient Selection in the CREST-2 Trial: Stenosis and Plaque Characteristics. International Stroke Conference, 2024. Stroke. 2024 (accepted for publication)
- Meschia JF, Lal BK, Howard G, Jones M, Heck D, Turan TN, Roubin GS, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar RM, Moore WS, Benson RT, Voeks JH, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2024. Stroke. 2024
- Chaturvedi S, Howard G, Meschia JF.Carotid Endarterectomy for Asymptomatic Stenosis. JAMA Internal Medicine. 2015;175:1242. (letter to the editor)
- Chaturvedi S, Rothwell P. Neurology. 2016;86:494-495. (letter to the editor)
- Chaturvedi S, Barrett K, Brott TG, Munster AB, Franchini AJ, Qureshi MI, Thapar A, Davies AH.Temporal Trends in Safety of Carotid Endarterectomy in Asymptomatic Patients: Systematic Review. Neurology. 2016;86:312-13. (letter to the editor)
- Brott TG, Meschia JF, Lal BK. Carotid Endarterectomy Should Not be Based on Consensus Statement Duplex Velocity Criteria. Journal of Vascular Surgery. 2016;63(6):141S. (editorial)
- Meschia JF, Brott T. Lessons From ACST-2. Stroke. 2022;52. Electronic publication ahead of print. (editorial) PMCID: PMC8960366
- Meschia, JF, Brott T. COVID-19, Contrast, and CREST-2: A Survey of Investigators. Stroke: Vascular and Interventional Neurology. 2022 Nov;2(6) [PMID: 36590385] [PMCID: PMC9799150] (research letter)
- Brott TG, Meschia JF, Lal BK, Chamorro A, Howard VJ, Howard G. When will we have what we need to advise patients how to manage their carotid stenosis? Lessons from SPACE-2. Stroke 2023;54:1452-1456. [PMID: 36942589] [PMCID: PMC10133171] (commentary)
- Lal BK, Brott TG, Edwards LJ, Meschia JF. CREST-2 Reaches a Surgical Milestone. Journal of Vascular Surgery 2023 (editorial), Available online 29 October 2023.
- Lal BK, Lazar RM, Edwards LJ, Brott TG, Meschia JF. Integrating cognitive testing as an outcome in carotid revascularization trials. Clinical Therapeutics 2023 (letter to the editor), Available online 7 December 2023.
- Meschia JF, Edwards LJ, Roubin G, Brott TG, Lal BK. CREST-2 Commitment to Rigorous Assessment of Carotid Stenting for Primary Prevention of Stroke. Stroke: Vascular and Interventional Neurology 2023 (research letter), submitted.
- Turan TN, Meschia JF, Lal BK. Antihypertensive pharmacotherapy for patients undergoing carotid revascularization. Annals of Vascular Surgery 2023 (letter to the editor), in press.
CREST-2 Manuscript PDFs
| strokeaha.122.042172.pdf |
| crest-2_publications_list_2021_10.pdf |
| lazar_et_al._baseline_cognition_in_crest-2.stroke_2021.pdf |
| meschia_the_crest-2_experience_with_the_evolving_challenges_of_covid-19_a_clinical_trial_in_a_pandemic.pdf |
| lal_racedifferencesinhighgradecarotidarterystenosis__stroke_.pdf |
| turan_rationale_design_and_implementation_of_intensive_risk_factor_treatment_in_crest2.pdf |
| lal_quality_assurance_for_carotid_stenting_in_the_crest-2_registry.pdf |
| lal_factors_influencing_credentialing_of_interventionists_in_the_crest-2_trial.pdf |
| moore_issues_to_be_addressed_angiology.pdf |
| marulanda-londoño_stroke_due_to_large_vessel_neurol_clin_pract_2016.pdf |
| chaturvedi_the_urgent_need_for_contemporary_neurology_2016.pdf |
| howard_crest2_protocol_manuscript__int_j_stroke_2017.pdf |
| demaerschalk_crest-2_site_selection_paper_stroke.pdf |
| lal_clinical_need_design_and_goals_for_the_carotid_revascularization_svs.pdf |
| heck_asymptomatic_carotid_stenosis_neurology_2017.pdf |
| meschia_evaluation_and_management_of_atherosclerotic_mcp.pdf |
| health_screening_program_and_crest2_lal_et_al_stroke_2022.pdf |
CREST-2 Manuscript Proposal Form
| crest-2_manuscript_proposal_form_update.docx |