Manuscripts, Abstracts, & Letters to the Editor
​

 Manuscripts 
  1. Moore W. Issues to Be Addressed and Hopefully Resolved in the Carotid Revascularization Endarterectomy Versus Stenting Trial 2. Angiology. 2016;67:408-10.
  2. Marulanda-Londono E, Chaturvedi S. Stroke due to large vessel atherosclerosis. Neurol Clin Pract. 2016;6:252-258.
  3. Chaturvedi S, Chimowitz M, Brown RD Jr, Lal BK, Meschia JF. The urgent need for contemporary clinical trials in patients with asymptomatic carotid stenosis. Neurology. 2016;87:1-8.
  4. Howard VJ, Meschia JF, Lal BK, Turan T, Roubin G, Brown RD Jr, Voeks J, Barrett KM, Demaerschalk BM, Huston III J, Lazar R, Moore W, Wadley VG, Chaturvedi S, Moy CS, Chimowitz M, Howard G, and Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: Protocol of the CREST-2 Clinical Trials. International Journal of Stroke, 2017. (accepted for publication)
  5. Demaerschalk BM, Brown RD, Roubin GS, Howard VJ, Cesko E, Barrett KM, Longbottom ME, Voeks JH, Chaturvedi S, Brott TG, Lal BK, Meschia JF, Howard G, for the CREST-2 Investigators. Predictors of Time to Site Activation, Randomization, and Enrollment Performance in a Multicenter Stroke Prevention Clinical Trial. (accepted for publication)
  6. Lal BK, Meschia JF, Brott TG. Clinical need, design, and goals for the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis trial. Seminars in Vascular Surgery. 2017. 30:2-7.
  7. Heck DV, Roubin GS, Rosenfield KG, Gray WA, White CJ, Jovin TG, Matsumura JS, Lal BK, Katzen BT, Dabus G, Jankowitz BT, Brott TG. Asymptomatic carotid stenosis: Medicine alone or combined with carotid revascularization. Neurology. 2017;88:2061-2065.
  8. Meschia JF, Klaas JP, Brown RD Jr, Brott TG. Evaluation and Management of Atherosclerotic Carotid Stenosis. Mayo Clinic Proceedings. 2017;92(7):1144-1157. 


Abstracts
  1. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update.American Neurology Association, 2014. Ann Neurol. 2014.
  2. Meschia JF, Lal BK, Howard G, Roubin G, Mackey A, Hill MD, Silver F, Demaerschalk BM, Brown RD Jr, Chimowitz M, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update.Canadian Stroke Congress, 2014.  Stroke. 2014;45(12): e25.
  3. Lal BK, Rosenfield K, Furlan A, Heck D, Tunis S, Roubin G, Meschia JF, Howard G, Brott TG, for the CREST-2 Investigators. CREST-2 Companion Registry Update. ISET. 2015.
  4. Huston III J, Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Society of Neuroradiology (ASNR). 2015.   
  5. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2015. Stroke. 2015.
  6. Lal BK, Rosenfield K, Heck D, Tunis S, Furlan A, Roubin G, Meschia JF, Howard G, Brott TG, for the CREST-2 Investigators. The CREST-2 Companion Registry: quality control for stenting and pathway to re-imbursement. International Stroke Conference, 2015. Stroke. 2015.
  7. Barrett KM, Moy C, Brown RD Jr, Broderick J, Spilker J, Linke M, Lal BK, Howard G, Brott TG, Meschia JF, for the CREST-2 Investigators. CREST-2 and StrokeNet Collaboration – Early Experience.International Stroke Conference, 2015. Stroke. 2015.
  8. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update. American Neurology Association 2015. Ann Neurol. 2015
  9. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Status Update. American Heart Association Scientific Sessions. 2015.
  10. Lanzino G, Meschia JF, Lal BK, Howard G, Roubin GS, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz MI, Demaerschalk BM, Howard VJ, Huston III J, Lazar RM, Moore WS, Moy C, Turan TN, Voeks JH, Brott TG, for the CREST-2 Investigators.CREST-2:A Randomized Trial Comparing Carotid Revascularization and Medical Management as Treatment for Asymptomatic Carotid Stenosis. World Federal of Neurosurgical Societies. 2015.
  11. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2016. Stroke. 2016.
  12. Lal BK, Rosenfield K, Heck D, Chaturvedi S, Tunis S, Meschia JF, Moy C,Conley R, NordstromK, Morris H, Roubin G, Brott TG for the CREST-2 Registry.CREST-2 Registry- A Pathway to Quality Control for Carotid Artery Stenting.International Stroke Conference, 2016. Stroke. 2016.
  13. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators.American Indian Participation in Clinical Research: A Cultural Perspective Survey from a CREST-2 Site. American Academy of Neurology Annual Meeting, 2016. Neurology. 2016.
  14. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Neurological Association Annual Meeting, 2016. Ann Neurol. 2016.
  15. Demaerschalk BM, Brown RD, Howard VJ, Tom M, Longbottom ME, Voeks JH, Kadiric E, Meschia JF, and Brott TG for the CREST-2 Investigators.Selection and activation of sites in a large multi-center randomized clinical trial.International Stoke Conference, 2017. Stroke. 2017.
  16. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. International Stroke Conference, 2017. Stroke. 2017.
  17. Roubin G, Heck D, White C, Rosenfield K, Dabus G, Jovin T, Jankowitz B, Katzen B, Gray W, Matsumura J, Hopkins LN, Gamble D, Voeks JH, Luke S, Lal BK, Meschia JF, and Brott TG. Credentialing of Interventionists in a Large Randomized Trial. International Stroke Conference, 2017. Stroke. 2017.
  18. Barrett KM, Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar RM, Moore W, Moy C, Turan TN, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update.American Academy of Neurology Meeting, 2017. Neurology. 2017.
  19. Demaerschalk BM, Brown RD, Howard VJ, Tom M, Longbottom ME, Voeks JH, Cesko E, Meschia JF, and Brott TG for the CREST-2 Investigators.Selection and activation of sites in a large multi-center randomized clinical trial.American Academy of Neurology Meeting, 2017. Neurology. 2017.
  20. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Neurological Association Annual Meeting, 2017. Ann Neurol. 2017.
  21. Turan TN, Voeks J, Barrett KM, Brown, Jr RD, Chaturvedi S, Chimowitz M, Demaerschalk B, Emmady P, Howard G, Howard VJ, Huston J III, Jones M, Lal BK, Lazar RM, Meschia JF, Moore W, Moy CS, Roldan AM, Roubin GS, Brott TG for the CREST-2 Investigators. Relationship Between Risk Factor Control and Physician Specialty in the CREST2 Trial. International Stoke Conference, 2018. Stroke. 2018.
  22. Meschia JF, Barrett KM, Roubin G, Heck D, Jones M, Wechsler L, Rapp JH, Turan TN, Demaerschalk BM, Lal BK, Voeks J, Howard G, Howard VJ,  Brott TG for the CREST-2 Investigators. Control of vascular risk factors at baseline in CREST-2. International Stoke Conference, 2018. Stroke. 2018.
  23. Haley WE, Turan TN, Voeks JH, Meschia JF, Lal BK, Roubin G, Shawl F, and Brott TG. Patterns of Baseline Antihypertensive Medications in Patients with Asymptomatic Carotid Stenosis. National Kidney Foundation 2018 Spring Clinical Meeting. Am J Kidney Dis. 2018.
  24. Turan TN, Meschia JF, Voeks J, Barrett KM, Brown, Jr RD, Chaturvedi S, Chimowitz M, Demaerschalk B, Emmady P, Howard G, Howard VJ, Huston J III, Jones M, Lal BK, Lazar RM,Moore W, Moy CS, Roldan AM, Roubin GS, Brott TG for the CREST-2 Investigators. Relationship Between Risk Factor Control and Physician Specialty in the CREST2 Trial. American Academy of Neurology Annual Meeting, 2018. Neurology. 2018. 
  25. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Academy of Neurology Annual Meeting, 2018. Neurology. 2018. 
  26. Lazar RM, Wadley VG, Marshall RS, Howard G, Howard VJ, Meschia JF, Voeks JH, Yuan Y, Lal BK, Heck D, Jones M, Brott TG. Baseline cognitive function among participants in the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2). American Academy of Neurology Annual Meeting, 2018. Neurology. 2018.
  27. Meschia JF, Barrett KM, Roubin G, Heck D, Jones M, Wechsler L, Rapp JH, Turan TN, Demaerschalk BM, Lal BK, Voeks JH, Howard G, Howard VJ, Brott TG for the CREST-2 Investigators. Control of vascular risk factors at baseline in CREST-2. American Academy of Neurology Annual Meeting, 2018. Neurology. 2018. 
  28. Howard VJ, Wadley VG, Wolff P, Zhang Y, Knopman D, Lal BK, Meschia JF, Voeks JH, Howard G, Brott TG, Lazar R. Methods, Successes and Lessons Learned from Centralized Cognitive Assessment in a Multicenter Clinical Trial of Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis (CREST-2). Society for Clinical Trials Annual Meeting, 2018. SCT Journal. 2018
  29. Linke M, Brott TG, Pivovarova E, Meschia JF, Luke S, Roll S, Broderick J. Single IRB Review and                                  Improves Approval Times for a NIH-funded Multi-Site Study. PRIM&R 2018 Advancing Ethical Research Conference. 2018
  30. Meschia JF, Lal BK, Howard G, Roubin G, Brown RD Jr, Barrett KM, Chaturvedi S, Chimowitz M, Demaerschalk BM, Howard VJ, Huston III J, Lazar R, Moore W, Moy C, Turan T, Voeks J, Brott TG, for the CREST-2 Investigators. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis: CREST-2 Update. American Neurological Association Annual Meeting, 2018.  
  31. Turan TN, Chimowitz MI, Roldan A, LeMatty T, Haley WE, Lopes-Virella M, Voeks JH, Zhang Y, Chaturvedi S, Foster M, Sharma M, Mehta R, Bradley N, Shaw F, Dobrovolny CL, Magee T, Lazar R, Meschia JF, Lal BK, Howard G, Howard VJ, Brott TG, for the CREST2 Investigators. Multimodal Risk Factor Management in Two Parallel Trials Comparing Revascularization with Intensive Medical Therapy for Asymptomatic Carotid Stenosis. Oral abstract presented at 34th World Congress of Internal Medicine, 2018.
​
Other 
  1. Chaturvedi S, Howard G, Meschia JF.Carotid Endarterectomy for Asymptomatic Stenosis. JAMA Internal Medicine. 2015;175:1242. (letter to the editor)
  2. Chaturvedi S, Rothwell P. Neurology. 2016;86:494-495. (letter to the editor)
  3. Chaturvedi S, Barrett K, Brott TG, Munster AB, Franchini AJ, Qureshi MI, Thapar A, Davies AH.Temporal Trends in Safety of Carotid Endarterectomy in Asymptomatic Patients: Systematic Review. Neurology. 2016;86:312-13. (letter to the editor)
  4. Brott TG, Meschia JF, Lal BK. Carotid Endarterectomy Should Not be Based on Consensus Statement Duplex Velocity Criteria. Journal of Vascular Surgery. 2016;63(6):141S. (editorial)
crest-2_publications_list_02.14.18.pdf
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CREST-2 Manuscript PDFs

moore_issues_to_be_addressed_angiology.pdf
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marulanda-londoño_stroke_due_to_large_vessel_neurol_clin_pract_2016.pdf
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chaturvedi_the_urgent_need_for_contemporary_neurology_2016.pdf
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howard_crest2_protocol_manuscript__int_j_stroke_2017.pdf
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demaerschalk_crest-2_site_selection_paper_stroke.pdf
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lal_clinical_need_design_and_goals_for_the_carotid_revascularization_svs.pdf
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heck_asymptomatic_carotid_stenosis_neurology_2017.pdf
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meschia_evaluation_and_management_of_atherosclerotic_mcp.pdf
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CREST-2 Manuscript Proposal Form
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crest-2_manuscript_proposal_form11.27.18.pdf
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